MegaMune™ is a triple action formula that can help maintain a healthy immune response for any time of year.

This daily supplement supports the immune system with some of its most basic, yet vital, functions like immune surveillance, and other aspects of a healthy immune response. Plus, MegaMune™ ingredients have antioxidant properties and help diversify the gut microbiome – otherwise known as the master control center of overall human health.



The immune system operates with two arms: the innate and adaptive branches.

The innate immune response is rapid and can occur within 4 hours of immune activation. However, innate immune reactions are not very specific and can affect our own tissue in the body!

The adaptive immune response, on the other hand, is slower to respond. However, when it is activated, it is extremely precise and thus much gentler on host tissues. MegaMune™ supports the adaptive immune response by promoting T-helper cell production, such as CD4+ and CD8+ cells.

The key to maintaining a healthy immune response is dictated by the gut microbiome which helps balance both adaptive and innate immunity. In fact, the gut is home to about 70% of immune cells and acts as the mother board of the entire immune system. The combination of green tea extract and fruit polyphenols were added to MegaMune™ in order to enhance microbial diversity within the powerful gut microbiome.

MegaMune™ is formulated with immune soothing ingredients to help maintain a healthy immune response.** For example, green tea extract promotes T-regulatory cells that help calm and balance the immune system.8 Other synergistic ingredients like selenium, sulforaphane, cranberry polyphenols, and pomegranate polyphenols can support the body’s natural detoxification process.9-12


MegaMune™ provides robust immune support that targets the immune system both on the cellular level and within the microbiome to provide a solid immune foundation. Take MegaMune™ any time of the year to keep your body vibrant and strong no matter what the outside world throws at you!

**These statements have not been evaluated by the Food and Drug Administration. 
This product is not intended to diagnose, treat,cure, or prevent any disease.


MegaMune Ingredients

Zinc — supports T lymphocyte activation, IgG production, and macrophage function

Selenium — Antioxidant properties, Supports T-helper cells

Echinacea Purpurea Extract — Supports white blood cells

Dried Yeast Fermentate — Antioxidant properties, Supports secretory IgA and NK cells

Green Tea Extract — Antioxidant properties, Supports Treg cells and NK cells

Broccoli Seed Extract — Antioxidant properties, Supports NK cell and B cell formation, Inhibits inflammatory NF-kB cascades, Supports Phase II detoxification pathways

Urophenol Cranberry Extract — Antioxidant properties, Supports microbial diversity

Pomanox Pomegranate Extract — Antioxidant properties, Supports microbial diversity and mitophagy

1 RERKSUPPAPHOL S, ET AL.   A randomized controlled trial of zinc 
supplementation in the treatment of acute respiratory tract infection
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2 SCIENCE M, ET AL.  Zinc for the treatment of the common cold: a 
systematic review and meta-analysis of randomized controlled trials.
CMAJ. 2012;184(10):E551­E561.

3 HO‑MANN PR, BERRY MJ.  The influence of selenium on immune responses.
Mol Nutr Food Res. 2008;52(11):1273­1280. doi:10.1002/mnfr.200700330 

4 HUDSON J, VIMALANATHAN S.  Echinacea—A Source of Potent Antivirals
for Respiratory Virus Infections. Pharmaceuticals (Basel). 

5 JENSEN, G. S, ET AL. Double-Blind Placebo-Controlled, Randomized 
Pilot Study: Consumption of a High-Metabolite Immunogen from Yeast 
Culture has Beneficial E‑ects on Erythrocyte Health and Mucosal 
Immune Protection in Healthy Subjects. The Open Nutrition 
Journal 2008, 2, 68-75.

6.MOYAD, ET AL. Effects of a modified yeast supplement on cold/flu 
symptoms. Urol Nurs 2008, 28 (1), 50-5.  

7 MOYAD, ET AL. Immunogenic yeast-based fermentate for cold/flu-like
symptoms in nonvaccinated individuals. J Altern Complement Med. 
2010, 16 (2), 213-8.

RICHARD S. BRUNO, EMILY HO.  Induction of regulatory T cells by 
green tea polyphenol EGCG. Immunology Letters, 2011;
DOI: 10.1016/j.imlet.2011.04.009 

9 LIANG, ET AL.  Sulforaphane Inhibits Inflammatory Responses of 
Primary Human T-Cells by Increasing ROS and Depleting Glutathione. 
Frontiers in Immunology. 2018; 9:2584.

10 BLUMBERG JB, ET AL. Impact of Cranberries on Gut Microbiota and
Cardiometabolic Health: Proceedings of the Cranberry Health Research
Conference 2015. Advances in Nutrition:
An International Review Journal. 2016;7(4).

11 ANHÊ FF, ET AL.  Apolyphenol-rich cranberry extract protects from
diet-induced obesity, insulin resistance and intestinal inflammation
in association with increased Akkermansia spp. population in the
gut microbiota of mice. Gut 2015;64:872–83.

12 LI Z, SUMMANEN PH, KOMORIYA T, ET AL.  Pomegranate ellagitannins
stimulate growth of gut bacteria in vitro: Implications for prebiotic
and metabolic effects. Anaerobe. 2015;34, 164–168.


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