Consequences of Leaky Gut

Lеаkу gut syndrome, also called Increased Gut Permeability, a diѕоrdеr саuѕеd by thе increased lеаkinеѕѕ оf intеѕtinаl mucosal mеmbrаnе, can have ѕоmе serious consequences if lеft unattended. Physicians think that treatment орtiоnѕ аrе diverse and limited in efficiency. They also think that there is ѕtill ѕоmе advantage tо соntrоlling or mаnаging thiѕ gаѕtrоintеѕtinаl problem whеn it comes tо рrеvеnting complications lаtеr оn.

What sticks out are the words “limited efficiency” and “controlling or managing” this problem. My personal experience shows leaky gut, which lead to the development of the autoimmune immune disease Hashimoto Thyroiditis, and severe food sensitivities, can be healed. After eliminating the foods my body was reacting to, especially eggs, eradicating pathogens, implementing meditation, using herbal supplements and spore biotics to support my bodies ability to heal the gut, I can report that I do NOT have any GI problems anymore. But back to the consequences of leaky gut.

Autоimmunе Diseases Due Tо Leaky Gut

Autоimmunе disorders occur whеn thе bоdу’ѕ immunе system (or ‘роliсеmаn сеllѕ’) turn аgаinѕt itѕ оwn hеаlthу tiѕѕuе, mistakenly thinking thеу аrе harmful раthоgеnѕ or fоrеign protein nееding еliminаtiоn. The result iѕ that thе bоdу’ѕ оwn рrоtесtivе mесhаniѕm turns аgаinѕt itѕеlf, creating havoc and can cause damage in all kinds of tissues.

Thеrе are a whоlе range оf diѕеаѕеѕ thаt fall under thiѕ саtеgоrу оf autoimmune diѕоrdеrѕ inсluding luрuѕ, rhеumаtоid arthritis, mixed соnnесtivе tiѕѕuе disease, Crоhn’ѕ disease and еvеn ѕоmе forms оf аrthritiѕ аnd diabetes.

Thе importance оf thе intestinal system in provoking and еxасеrbаting thеѕе autoimmune соnditiоnѕ has bееn rесоgnizеd lаtеlу аnd рhуѕiсiаnѕ treating раtiеntѕ with thеѕе diѕоrdеrѕ аrе bеginning tо take note of the role thаt Leaky Gut Sуndrоmе рlауѕ in it.

Othеr Diѕеаѕеѕ Cаuѕеd Bу Leaky Gut

Leaky gut syndrome саn со-еxiѕt аlоng with оthеr hеаlth рrоblеmѕ, many оf whiсh аrе wоrѕеnеd without repairing a leaky gut. A fеw оf thеѕе аѕѕосiаtеd diѕеаѕеѕ inсludе:

  • Eczema, рѕоriаѕiѕ аnd several other dermatologic conditions

  • Pancreas dеfiсiеnсу lеаding to mаlаbѕоrрtiоn and diаbеtеѕ

  • Fungal аnd yeast infесtiоnѕ such аѕ candida infestation

  • Mаlnutritiоn ѕесоndаrу to failure of absorption оf nutriеntѕ

  • Sеnѕitivitу tо ѕеvеrаl chemicals and аdditivеѕ саuѕing аllеrgiеѕ

  • Fаtiguе, tiredness, аnd a fаilurе tо thrive in сhildrеn

  • Frequеnt hеаdасhеѕ аnd inаbilitу tо concentrate on wоrk

  • Lоѕѕ оf memory and easy fоrgеtfulnеѕѕ аrе соnѕеԛuеnсеѕ

  • Bowel disturbances lеаding tо diаrrhеа аnd irrеgulаr hаbitѕ

  • Anxiety

Whеn Lеаkу Gut Syndrome affects сhildrеn, thе рrоblеmѕ аrе соmроundеd bу the requirеmеnt fоr highеr lеvеlѕ of nutriеntѕ in diet fоr уоungѕtеrѕ аѕ wеll as the lоng tеrm consequences оf сhrоniс infесtiоnѕ аnd malnutrition. Vассinаtiоn has led tо a similar syndrome like lеаkу gut in some сhildrеn.

Livеr Diѕоrdеrѕ Rеѕulting From Leaky Gut

With thе liver bеing thе firѕt mаjоr barrier tо tоxinѕ thаt еntеr thе blооd ѕtrеаm thrоugh leaky gut mеmbrаnеѕ, it is nоt ѕurрriѕing that thе liver iѕ affected аt ѕоmе stage or the оthеr in реорlе with leaky gut ѕуndrоmе.

Sоmе tоxinѕ mау еѕсаре thе ѕсаvеnging еffесt of thе liver, аnd еntеr thе general circulation саuѕing harm in ѕеvеrаl tissues. But most оf thеm gеt trарреd by thе livеr, whеrе thеу are nеutrаlizеd аnd еxсrеtеd in bilе. Hоwеvеr, this increased lоаd on thе livеr can ѕоmеtimеѕ lеаd tо mаlfunсtiоn, оr even frank livеr fаilurе, thоugh these аrе extreme соmрliсаtiоnѕ that hарреn only in a very tinу minority of ѕuffеrеrѕ.

See my article on liver detoxification here.

What could pass the gut lining and enter the hepatic portal vein?

  • Toxins, environmental; from bacteria and viruses
  • Larger, partially digested food particles
  • Histamine
  • Zonulin, Bacteria secret toxins and can alter tight junctions.

The increased gut permeability happens at the microvilli, which are finger like structures and single layer of cells. The microvilli reach into the gut and have the job to let the nutrients and vitamins, extracted from digested food, into the blood stream which leads to the hepatic portal vein. This vein brings the nutrients, vitamins, and toxins into the liver for detoxification.

In a healthy gut the single cell layer of the microvilli are held together with proteins called tight junctions. When digested food reaches the microvilli, the tight junctions loosen up just so much that the nutrients can get into the blood stream. Zonulin regulate the opening and closing of the tight junctions.

The question then is How can we prevent and heal a Leaky Gut?

  • Identify and Remove inflammatory foods from your diet

MRT food sensitivity test, IgG, IgM, IgE antigen blood test

      • Eat organic foods if possible to avoid chemicals. At least wash fruits and vegetables with water and vinegar. Peal fruits.
      • Drink enough water to prevent dehydration. Water is necessary for phase II detoxification.
      • Identify and Remove pathogens in the gut, such as parasites using a stool pathogen test. Blood tests for virus antibodies. CBC with diff to check if the immune system is overactive.
      • A better option would be to restore gut function with the 3 Step Gut Restoration Program.
      • You also can listen to my Youtube video on the 3 Step Gut Restoration Program

    • Reduce Stress: don’t over commit, learning to say NO can be very important.
    • Reduce EMF exposure; turn wifi off at night (Check out my Youtube channel on this subject)
    • Don’t use a cell phone and/or computer at night before you go to bed. The blue light emitted by the screen of those devices prohibit melatonin production.
    • Sleep in a dark, cool room

If you have any questions, can contact me.

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Reference:


Zonulin signaling http://en.wikipedia.org/wiki/Zonulin

The gastrointestinal tract microbiome, probiotics, and mood.   Vitetta L1, Bambling M, Alford H.

Abnormal intestinal permeability and microbiota in patients with autoimmune hepatitis.

Lin R1,Zhou L1,Zhang J1,Wang B1.

Arthritis susceptibility and the gut microbiome. Taneja V1.

Leaky gut and autoimmune diseases. Fasano A1.

Gut permeability is related to body weight, fatty liver disease, and insulin resistance in obese individuals undergoing weight reduction.    Damms-Machado A1, Louis S1

Abnormal Barrier Function in Gastrointestinal Disorders.   Farré R1,2, Vicario M3,4,5.

Weight Gain – Weight loss – Gut Bacteria

Obesity can cause major health issues such as diabetes and

cardiovascular disease.

 

Now, the question is how much do lifestyle, diet and the microbiome (gut bacteria) play a role in this?

Scientists have found that gut bacteria play a key role in digestion and fat absorption, even in the amount of calories one absorbs from food. That is why some people can eat whatever they want and how much they want and never really gain weight while others eat a restricted diet and still gain weight.

Order Megasporebiotic

Two groups of gut bacteria

Bacteroidetes and
Firmicutes

have been studied in mice in regard to obesity.

Scientists took two groups of sterile mice, meaning they killed all bacteria in the mice’s gut prior to the experiment, and reintroduced firmicutes and bacteroidetes in different ratios.

The mice with a greater amount of firmicutes gained weight and actually ended up being obese in comparison to the other mice with less firmicutes, while both groups ate the same food.

What happens is that firmicutes are able to extract more calories from food in the form of fatty acids.

Also, the kind of food you eat will cause a shift in the microbiota. Eating meals high in bad fats, such as vegetable oils, and high calories, leads to the die off of gram negative bacteria and specifically a die off of bacteroidetes.

Bacteroidetes are the kind you want more of in the gut in comparison to the firmicutes if you want to stay lean.

A high fat and a high caloric diet causes the die off of gram-negative bacteria.   When they die, they release Lipopolysaccharides (LPS) from the outer layer of the cell.

The German physician and bacteriologist Richard Pfeiffer (1858 – 1945) discovered those LPS’s and coined the term “endotoxin”.

Endotoxins are kept in the bacterial cell and only released when the cell wall is destroyed.

Now, those endotoxins cause gut inflammation and the loosening of the tight junction which hold the cells of the gut lining together. Leaky gut causes long term inflammatory responses which changes the microbiome and the person ends up with the formation of an obese gut flora.

The obese microbiome determines your cravings, how much you eat, and extracts more calories out of the food you eat.

Lifestyle change by itself is simply not enough to overcome weight gain and inflammation.

Exercise for example counts only about 20 % toward weight loss while

Diet counts about 80 %.

There Is HOPE

for someone who is overweight and has trouble losing weight.

Dietary changes toward a healthy diet with healthy fats, fiber rich foods, and less calories can change the microbiom within 24 hours.

References

(1) Overweight and obese adults (self-reported), 2011, Statistics Canada, http://www.statcan.gc.ca/pub/82-625-x/2012001/article/11664-eng.htm (October 29, 2012)

(2) Ley, R.E., Turnbaugh, P.J., Klein, S., and Gordon, J.I. (2006). Microbial ecology: human gut microbes associated with obesity. Nature 444, 1022– 1023.

(3) Semova, I., Carten, J.D., Stombaugh, J., Mackey, L.C., Knight, R., Farber, S.A., and Rawls, J.F. (2012). Microbiota Regulate Intestinal Absorption and Metabolism of Fatty Acids in the Zebrafish. Cell Host Microbe 12, 277-288.

(4) Backhed, F., Ding, H., Wang, T., Hooper, L.V., Koh, G.Y., Nagy, A., Semenkovich, C.F., and Gordon, J.I. (2004). The gut microbiota as an environmental factor that regulates fat storage. Proc. Natl. Acad. Sci. USA 101, 15718–15723.

Probiotics – the Truth and the Misconception of Re-Seeding the Gut

 Probiotics being used to Re-Seed the Gut  

The hypothesis of the probiotic industry is that we can re-seed the gut with the good bacteria. They use the same model as we would re-seed a bare spot in our lawn. You take a few grass seeds, sprinkle it on the dirt, water, fertilize and it grows back to a full lush lawn.

Taking probiotics orally with factory grown strains of bacteria to re-seed the gut is simply

NOT

 possible

You probably heard about the Human Microbiome Project, which taught us a lot about the microbiota which we didn’t know before.

What do we know about Probiotics?

  • We know that they keep the bad bacteria in check
  • We know that we receive ALL of the lactobacillus and bifidobacterium species that we currently have in our gut, from our mother. They are called commensal bacteria.
  • We know that we receive those bacteria during child birth by passing through the vagina, through mother’s milk, through skin to skin contact with our mother, father and other family member.
  • We know that after 838 days after birth, we have our own, unique set of gut microbes, which is basically our adult microbiota.
  • We know that food influences the gut microbiota for the better or worse.
  • We know that our lifestyle influences the microbiome. Stress would be a negative influence, while relaxation would be a positive.
  • We know that antibiotics kill all kinds of strains in the gut, the good and the bad.

How did our Ancestors get their Probiotics?                                                  

  • Our ancestors lived from the land as hunters and gatherers
  • They searched for roots. They had to dig up the dirt to get to them and were exposed to lots and lots of bacteria and spores that lived in the dirt.
  • They did not go home and scrub their hands and cleaned their fingernails to get rid of bacteria
  • They did not use anti-bacterial soap or gels
  • They ate the animals they hunted which ate the natural grass
  • So our ancestors were exposed to environmental organisms every day

Bacillus species

Megasporebiotic

You may know that we humans are more bacteria then human.

Let me explain. We have about 10 trillion human cells in our body and 100 trillion bacterial cell.

So Bacterial genes outnumber human genes 150 to 1 (25,000 human genes vs. 3.3 million microbial genes.

One of these species is the Bacillus species.

They live in the human gut and use the environment in spore form as a place to transfer from host to host.

This means they can live in an aerobic, which is the environment, as well as in an anaerobic world, the GI tract.

Bacteria love the GI tract; it is warm, moist, and provides lots of food.

Benefit of a healthy microbiome in particular the Bacillus Species

  • They train and modulate the immune system by stimulating the lymphoid tissue in the gut. Bacillus species help to improve T and B- cell function and the adaptive immune system and reduce inflammatory processes.
  • They help us digest food. Protease, peptidase, lipase, cellulose, amylase, lipase, lactase and pectinase are probably familiar names to you. You probably have a digestive enzyme supplement at home that includes all or some of those.  Guess what, Bacillus species produce those digestive enzymes I listed above. They also digest starches and non-starch polysaccharides (cellulose from plants such as broccoli) without producing any gas.
  • They help balance the microbiota. Bacillus species keep harmful bacteria in check and they produce nutrients that are designed specifically to feed the healthy microbes. In other words, they create a healthy environment in our gut where the good guys can flourish and do their job while the bad guys are being eliminated and held in check.
  • They produce nutrients in the gut. B vitamins are produced by bacillus species. As you know those are important for the nervous system as well as key methylation functions. Vitamin K2 is also produced by gut bacteria which is important for heart and artery health but mostly used by the bacteria themselves.
  • They produce short-chain fatty acids (SCFAs) which are very important to keep the gut healthy. They dampen inflammation and prevent leaky gut.

Megaspore is the first probiotic that includes 5 critical Bacillus species in spore form.

As we just learned Bacillus species live as spores in the environment and come out of the spore form in the GI tract.

The improvement in health, gut function, even behavioral changes of children, elimination of allergies we see in people using Megaspore is remarkable.

For even more information and to purchase MegaSpore click here and here 

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Doreen, NC
This has been a year of learning experiences. I have gone to several doctors over the years. And each time I have come away frustrated with all of them. They don’t listen or they hear what they want. I have listened to their advice and stuck with it for years. I was on BP meds, two diabetic medications, and Cholesterol meds. when I met Linda. Linda told me things no one had ever mentioned before. She told me that from the test results I gave her that I was probably sensitive to Gluten and had leaky gut issues. She worked up a protocol and supplements for me. I changed my diet with Linda’s help and the results were incredible. I have lost over 50 pounds but, more important than that is I feel so much better. My children have only known me as a large (size 20-22) person. They are getting used to the new and happier (size 10) person I am now. I am off both diabetic meds and cholesterol meds. My BP meds have been lowered. Linda is very caring, listens to you and answers all your questions. She is diligent when giving you advise. She is a wealth if information. My suggestion for everyone is to listen to Linda’s suggestions and advise, and as the saying goes “Just do it.” Thank you so much Linda.
Rich, CA
I was suffering from chronic cystic acne around my chin before working with Linda. I would try and keep a food journal to try and figure out what I was eating that was causing this debilitating condition. The problem is that food sensitivities can show up 72 hours later, and it was too hard to figure out which food item it was. I finally decided to just work with Linda and take the MRT test. I had enough of guessing what foods were causing the cystic acne. When I got the results back, I was surprised about the items I tested sensitive to. I simply removed all those items from my diet, and my face got to its clearest in years within three weeks! No more painful nodules on my face! I’ve noticed that if I eat items from my list, I can feel a reaction on my face coming, so I know the test is accurate. I just stop eating those items, and my face clears again. I highly recommend working with Linda. She is very attentive to detail, and is committed to you having the best results for your condition related to diet. I only wish I did this earlier.


Elfriede, Germany
I’m so happy to report that the inflammation in my knee is gone and I am able to walk without a cane. Linda recommended to get off gluten and gave me the right kind of supplements. I am 88 years old and not being dependent on a cane is the best thing that happened to me in a long time. I have more energy, can think better, can clean my apartment and cook my own meals.