Correct Thyroid Blood Test

Why would a physician not order the correct thyroid blood test?

Recently I saw a PA, after the car accident I was involved in, to get my thyroid panel done.

You all know that stress influences the Hypothalamus-Pituitary-Adrenal axis and H-P-Thyroid axis in a negative way which can cause low adrenal function as well as low thyroid hormone output.    (if you don’t know what the HPA-HPT axis is, please go to my website, contact me and ask for the ebook on Hypothyroidism).

So, I asked the PA to run a thyroid panel and knowing that most of them don’t order the correct tests, I also asked which blood markers she would usually run.

Her reply was that she tests the TSH and Free T4.

To my request wanting the Free T3 and TPO antibodies as well, she said:  You don’t need the Free T3 and why would you like to the TPO antibodies tested?

I asked her why she thinks that the Free T3 doesn’t need to get tested.

You will not believe her answer: Free T3 is not important since the active form of thyroid hormone is Free T4. The thyroid produces Free T3 which gets converted into Free T4. WHAT?

I almost exploded and told her that Free T3 is the active thyroid hormone, which enters the cells and is necessary in every cell of the body.

She insisted that her statement was correct and told me that I got this backwards.

I had a hard time composing myself and just replied “you got this backwards and I would suggest you read your medical books again.”

At the next visit she showed me on her phone the source of her knowledge about thyroid hormones. She mentioned it is Hypcrates.com  or something like that. It actually states that Free T3 is the main hormone produced by the thyroid gland which then is converted into Free T4.

I was speechless / well I also still suffered from dizziness from the concussion and just wanted to go home, so I didn’t want to get into a big discussion about her false information.

When I asked her if the lab results came in, she mentioned yes, they are normal. I told her the TPO antibodies can’t be normal yet. Her reply: They (whoever they is) don’t test the antibodies when the labs were normal.

I never ever heard of such a stupid explanation in all the years since I was diagnosed with Hashimoto’s.

So, what is going on here or with other physicians who just test the TSH, and antibodies only once to diagnose Hashimoto’s.

A friend of mine is an Endocrinologist in Switzerland. She told me that her textbook contained two (2) pages about Hashimoto Thyroiditis.

Well, that says it all. Our physicians usually have no knowledge about thyroid hormone conversion problems; therefore they don’t test the Free T3 or reverse T3.

They also wouldn’t know what to do if they would suspect a conversion problem, would they?

They only diagnose diseases and then prescribe drugs.

In regard to Hashimoto’s it means that they only have to test the TPO antibodies once to get paid by the health insurance for the hard work they did on their patients.

After that they just prescribe thyroid replacement hormones and if the blood levels of TSH, Total T4 and Total T3, maybe Free T4 are falling into the lab ranges, then they did their work and the patient should be fine and not complain.

My intention to get the TPO antibodies tested is based on the fact that I got them down from over 15K to 123. One year later they increased to 1400 and my best bet was the re-activation of   Epstein Barr Virus.  Ever since I knew this I was supporting my immune system in different ways which I will talk about in another newsletter.

My explanation for the inexcusable behavior of the PA is that the pharma industry is educating physicians to make even more profit and keep people sick, keep them on prescription drugs and make them coming back with more “side” effects to get more drugs.

In order to understand this part I suggest the interview by Sean Croxton with. Gerald Roliz, an Ex- pharma rep.

or contact me if you would like to book a free 20 minute Health Consultation.

Stop calling it Adrenal Fatigue. Call it HPA -Axis Dysfunction

Do you feel tired during the day and wired at night? Aren’t most of your friends and acquaintances complaining about being exhausted? Do you assume that this may be the norm?

Although it may be common for a lot of people to be tired most of the time it is not normal.

Symptoms associated with HPA axis dysfunction include:

  • Weight gain in the midsection
  • Fatigue, feeling of tiredness all the time or in the afternoon
  • Sleep problems, trouble falling asleep or staying asleep
  • Allergies, seasonal allergies, or food allergies
  • Depression, not being motivated
  • Memory problems, can’t remember where you parked your car or put your key
  • Visiting the restroom often
  • Constipation
  • Blood sugar problems, low blood sugar or high blood sugar
  • Blood pressure problems, feeling dizzy all of a sudden, legs feel heavy
  • Anxiety or nervousness, feeling jumpy
  • Brain fog, not being able to concentrate
  • Dry skin
  • Feeling cold all the time, or just having cold hands and feet
  • Loss of libido

Why do I call adrenal fatigue “HPA axis dysfunction”?

The adrenal glands produce hormones, especially cortisol as a stress hormone, which help us cope with daily stress. But they also help regulate blood sugar levels, and reduce inflammation. However, the adrenal glands do not work in a vacuum; they are connected via a hormonal feedback loop with the hypothalamus.

The Hypothalamus checks the level of hormones in the blood and sends hormonal signals (CRH) to the Pituitary which in return sends ATCH, a hormone, to the Adrenal glands to either reduce the production of cortisol or to elevate it. We call this connection the HPA axis.

HPA axis

Stress induces the release of corticotrophin releasing hormone (CRH)

CRH stimulates the release of drenocorticotropic hormone (ACTH) from the anterior pituitary

ACTH stimulates the release of glucocorticoids from the adrenal cortex

As you can see the interaction between the different hormone glands in the HPA axis is complex.

Remember, Cortisol is a stress hormone, therefore any kind of stress will elevate this very important hormone. If you suffer from chronic stress your adrenal glands will be constantly stimulated via the HPA axis.

Not only are adrenal gland hormones effected, but also the thyroid hormones through the HPA-HPT (T for Thyroid) axis. Remember, Cortisol is a Stress hormone. Therefore, any kind of stress will elevate this very important hormone. If you suffer from chronic stress your adrenal glands will be constantly stimulated via the HPA axis.

adrenal fatigue hpa axis

Moreover, chronic stress disrupts the glucocorticoid dynamics, modifies cortisol levels which disrupts the HPA-axis feedback loop and can have a negative impact on mood and neurotransmitter.

A simple dried urine test could help you determine your adrenal function if you produce too much or too little of the stress hormone cortisol and or estrogen, progesterone, testosterone, or melatonin. The dried urine test will also determine the hormone metabolites, but this needs to be explained in a separate article because it involves gene mutations and methylation processes.

Unfortunately, the medical community doesn’t really recognize HPA axis dysfunction as a serious condition. The problem lies in the way cortisol is being tested. The dried urine test measures cortisol four times a day while your doctor only measures cortisol in the blood one time during a particular day or in a 24 hour urine test of the total cortisol output.

If you get tested or not, my recommendation is to reduce external stress as much as possible, eat a whole food diet and get adequate sleep. If you suspect internal stressors such as pathogens or mineral imbalances, get tested.

Environmental stressors and epigenetic control of the hypothalamic-pituitary-adrenal-axis (HPA-axis) 
Richard Lee and Akira Sawa 

Role of the Hypothalamic-Pituitary-Adrenal Axis in Developmental Programming of Health and Disease Fuxia Xiong and Lubo Zhang

Toxins in Personal Care Products and the Environment

toxins in cosmetic

Toxins are present in the environment, drinking water, food, food containers and maybe cleaning products. Toxins can also be found in chemical ingredients that are used in personal care products. Care products we use every day such as shampoo, conditioner, hair styling products, body lotion, make up, foundation, facial creams, perfumes, and shaving cream have toxin in them. These chemicals can have impact on your body because your skin easily absorbs whatever you rub onto it – body lotion or magnesium gel.

There are certain chemicals which are often used in personal care products that could affect your health. These personal care products that contain some dangerous chemicals need be avoided. Let us look at some of these chemicals that could be hazardous to your health.

Parabens

There are certain chemicals that made up Parabens and these include Methylparaben and Propylparaben. These two chemicals are found in hair products, shaving cream, body lotion and cosmetics as antimicrobial preservatives. They act as endocrine disruptor and they interfere with estrogen activity and bind to alpha and beta estrogen receptor in female. Besides, these two chemicals increase the risk of breast cancer. They cause breast cancer because parabens mainly accumulate in breast tissue.

Phthalates

Phthalate has Ethylparaben, 4-Hydroxybenzoic acid and many other chemicals that could be dangerous. Phthalates are used in plastic bottles because they soften the material. Every personal care product that is sold in soft containers is being contaminated with phthalates. Phthalates are also found in frequencies, paint pigments and flooring as well as in plastic milk containers.

Phthalates are also endocrine disruptor with estrogenic activity. Women who suffer from endometriosis often times have elevated levels of phthalates as well as children on the autism spectrum. Phthalates are linked to birth defects, obesity, diabetes and heart disease.

These chemicals that made up Phthalate can decrease male fertility by lowering sperm count and testosterone. However, it is important to remember that the law in the USA does not require full disclosure of fragrance mixtures. Therefore, it is hard to know if the products you are purchasing contain phthalates or not. Phthalates are fat-soluble. Foods such as butter, milk and cheeses stored in plastic container have higher amounts of Phthalates than foods that do not contain fats.

Bisphenol-A

Bisphenol-A, also called BPA, is found in food containers especially food cans with epoxy lining. It can also be found even on some sales receipts. BPA is present in plastic containers with the #7 recycling code as well as in water bottles and sometimes in water supply pipes.

BPA exposure can occur through store receipts and personal care products. It often bypasses liver metabolism and thereafter enters the bloodstream directly. BPA is an endocrine disruptor with estrogenic activity. Foods such as butter, milk and cheeses stored in plastic container have higher amounts of BPA than foods that do not contain fats.

When BPA get into foods, it can cause a higher than normal risk for type II diabetes, interfere with infertility, increase the risk for cardiovascular disease, breast cancer, prostate and testicular cancer.

Perfluorinated Compounds PFC’s

These are teflon chemicals which repel oil and water and are basically indestructible. They are found in food packaging such as fast food wrappers, and of course in cookware coated with PFC’s. Furniture, carpets and clothing can be treated with PFC’s to become stain-resistance.

Effects of PFC’s on animal

PFC’s are hormone disruptors. Several studies conducted on animal revealed abnormal thyroid and testosterone levels after exposure to certain PFC’s. Other animal studies found that PFC’s can cause certain types of cancer such as kidney and testicular cancers.

According to pubmed, “Endocrine disruptors are chemicals that interfere with the hormone system and produce adverse developmental, reproductive, neurological, and immunological effects in mammals.” Further studies found that even substances that were banned a long time ago can be detected in the body of almost every tested animal and human. This can be explained by the fact that endocrine disruptors are highly lipid soluble which leads to their bio accumulation in adipose tissue. Estrogen disruptor acts on estrogen receptor sites in the cell nucleus as well as changing the expression of genes by binding to DNA.

Why chemicals are difficult to remove from the body

The liver is the number one detoxification organ in humans’ body. It works in two phases to get rid of waste products to keep us healthy. Phase I is the Hydroxylation phase where molecules such as hormones, neurotransmitter, drugs and toxins become activated. The enzyme CYP450 converts such molecules and those can act as carcinogens and free radicals.

In Phase II detoxification the liver inactivates and detoxifies the substances from Phase I. The waste products are sent via the bile into the intestines and can get re-absorbed into the liver. This is the stage it gets difficult to remove chemicals from the body.

Problems with the detoxification process can occur when we lack phytonutrients because we eat a poor diet. Fried foods, processed foods are especially harmful to the body. What we need are fresh vegetables and fruits, grass fed beef and free roaming chicken for proteins, fat, carbohydrates, vitamins, minerals and fiber.

Another reason why chemicals are difficult to get rid of has to do with gene variations that we are born with, which down or up regulate enzymatic activities. These enzymes metabolize estrogens.

Metabolism of estrogens is a complex process and can be monitored with a combination of gene test and a urine hormone test which also measures the metabolites of estrogen and other hormones.

What can you do to reduce your exposure to toxins?

If you are looking to get more information on how to reduce toxins generally, login to www.ewg.org      The Environmental Working Group’s

References: 
  • Charles, Ak, Darbre, Pd. Combinations of parabens at concentrations measured in human breast tissue can increase proliferation of MCF-7 human breast cancer cells. J Appl Toxicol. 2013; 33(5); 390-8
  • Dodge LE, Williams PL, Williams, Missmer SA, Souter I, Calafat AM, Hauser R, Associations, between paternal urinary phthalate metabolite concentrations and reproductive outcomes among couples seeking fertility treatment. Reprod Toxicol. 2015; Oct 6
  • Lin J, Chen W, Zhu H, Wang C. Determination of free and total phthalates in commercial whole milk products in different packaging materials by gas chromatography-mass spectrometry. J Dairy Sci. 2015; Oct 7
  • Naraanan KB, Ali M, Barclay BJ, et al. Disruptive environmental chemicals and cellular mechanisms that confer resistance to cell death. Carinogenesis. 2015; 36; S89-110
  • Urinary Paraben Concentrations and Ovarian Aging among Women from a Fertility Center / Kristen W. Smith Irene Souter, Irene Dimitriadis, Shelley Ehrlich, Paige L. Wiliams, Antonia M. Calafat and Russ Hauser
  • http://www.atsdr.cdc.gov/toxfaqs/tf.asp?id=900&tid=183
  • http://www.watoxics.org/chemicals-of-concern/perfluorinated-compounds-pfcs
  • http://www.watoxics.org/chemicals-of-concern/perfluorinated-compounds-pfcs
  • http://www.organicandhealthy.com/carpet.html