Gut health and the microbiome is in the center of health and well being. Find out what I’m talking about….
are non-digestible fibers that feed the bacteria living in your gut.
However, most prebiotics on the market can feed both harmful and beneficial gut bacteria. As you can see, this is not a good option if you already have an imbalance of the good and bad guys, which is called dysbiosis. You don’t want more of the bad guys; you want more of the good guys.
When you feed the bad bacteria, you can experience or even exacerbate digestive issues like gas, constipation, diarrhea, and / or cramping.
The population of the beneficial bacteria can be easily diminished by
- and other environmental toxins that enter our body through the water we drink, the air we breath.
You can purchase MegaPrebiotic here
What if you could count on a prebiotic that feeds
the good guys?
Microbiome Labs has developed a prebiotic that only feeds beneficial bacteria. Those keystone bacteria are Akkermansia muciniphila, Faecalibacterium prausnitzii, and Bifidobacteria
plays an important role in metabolism and has been shown to promote fat loss. Low levels of A. muciniphila have been associated with obesity, diabetes, liver disease, cardiometabolic diseases, and low-grade inflammation.**
can increase the production of butyrate, a short-chain fatty acid that can relieve intestinal inflammation. Low levels of F. prausnitzii have been associated with irritable bowel syndrome, inflammatory bowel diseases (IBD) like Crohn’s disease and ulcerative colitis, celiac disease, and chronic constipation.**
can also increase butyrate production and promote lean body mass. Low levels of Bifidobacteria have been associated with obesity, diabetes, celiac disease, allergic asthma, dermatitis, IBD, chronic fatigue syndrome, and psoriasis.**
Increasing populations of these protective bacteria is an integral part of reinforcing a healthy gut microbiome. Studies have shown that a more diverse gut microbiome is associated with a stronger immune system and a decreased risk for chronic illness.**
**These Statements have not been evaluated by the Food and Drug Administration (FDA)
is a cutting-edge Precision Prebiotic™ supplement made up of
- clinically-tested, non-digestible
- Oligosaccharides that can increase microbial diversity and selectively feed beneficial keystone bacteria like Akkermansia muciniphila, Faecalibacterium prausnitzii, Bifidobacteria.
The oligosaccharides are derived from
- non-GMO green and gold kiwi fruit,
- non-GMO corn cob, and
- rBST-free cow’s milk (rBST: recombinant Bovine Somatotrophin is a growth hormone).
The findings of these oligosaccharide studies are quite impressive and have shown that Akkermansia muciniphila population increases by 8,000% in 5 weeks, F. prausnitzii by 100% in 4 weeks, Bifido by 10% in 6 weeks.
Increasing populations of these protective bacteria is an integral part of reinforcing a healthy gut microbiome. Studies have shown that a more diverse gut microbiome is associated with a stronger immune system and a decreased risk for chronic illness.
MegaPreBiotic™ REINFORCES the beneficial microbial changes created by MegaSporeBiotic™ to promote a strong and diverse microbiome.**
MegaPreBiotic Dosing Instructions
Start with ½ scoop daily for one week, then increase to 1 scoop daily with or without food, or as directed by your healthcare practitioner.
Mix into 16 oz of cold water or liquid of your choice.
For more information on gut health you may be interested in the article I wrote a while back on the Consequences of Leaky Gut, which you can read here:
1) Blatchford P, Stoklosinski H, Eady S, et al. Consumption of kiwifruit capsules increases Faecalibacterium prausnitzii abundance in functionally constipated individuals: a randomised controlled human trial. J Nutr Sci. 2017; 6: e52. 2) Everard A, Lazarevic V, Derrien M, et al. Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice. Diabetes. 2011 Nov; 60(11): 2775–2786. 3) Yang J, Summanen PH, Henning SM, et al. Xylooligosaccharide supplementation alters gut bacteria in both healthy and prediabetic adults: a pilot study. Front Physiol. 2015; 6: 216.
Lеаkу gut syndrome, also called Increased Gut Permeability, a diѕоrdеr саuѕеd by thе increased lеаkinеѕѕ оf intеѕtinаl mucosal mеmbrаnе, can have ѕоmе serious consequences if lеft unattended. Physicians think that treatment орtiоnѕ аrе diverse and limited in efficiency. They also think that there is ѕtill ѕоmе advantage tо соntrоlling or mаnаging thiѕ gаѕtrоintеѕtinаl problem whеn it comes tо рrеvеnting complications lаtеr оn.
What sticks out are the words “limited efficiency” and “controlling or managing” this problem. My personal experience shows leaky gut, which lead to the development of the autoimmune immune disease Hashimoto Thyroiditis, and severe food sensitivities, can be healed. After eliminating the foods my body was reacting to, especially eggs, eradicating pathogens, implementing meditation, using herbal supplements and spore biotics to support my bodies ability to heal the gut, I can report that I do NOT have any GI problems anymore. But back to the consequences of leaky gut.
Autоimmunе Diseases Due Tо Leaky Gut
Autоimmunе disorders occur whеn thе bоdу’ѕ immunе system (or ‘роliсеmаn сеllѕ’) turn аgаinѕt itѕ оwn hеаlthу tiѕѕuе, mistakenly thinking thеу аrе harmful раthоgеnѕ or fоrеign protein nееding еliminаtiоn. The result iѕ that thе bоdу’ѕ оwn рrоtесtivе mесhаniѕm turns аgаinѕt itѕеlf, creating havoc and can cause damage in all kinds of tissues.
Thеrе are a whоlе range оf diѕеаѕеѕ thаt fall under thiѕ саtеgоrу оf autoimmune diѕоrdеrѕ inсluding luрuѕ, rhеumаtоid arthritis, mixed соnnесtivе tiѕѕuе disease, Crоhn’ѕ disease and еvеn ѕоmе forms оf аrthritiѕ аnd diabetes.
Thе importance оf thе intestinal system in provoking and еxасеrbаting thеѕе autoimmune соnditiоnѕ has bееn rесоgnizеd lаtеlу аnd рhуѕiсiаnѕ treating раtiеntѕ with thеѕе diѕоrdеrѕ аrе bеginning tо take note of the role thаt Leaky Gut Sуndrоmе рlауѕ in it.
Othеr Diѕеаѕеѕ Cаuѕеd Bу Leaky Gut
Leaky gut syndrome саn со-еxiѕt аlоng with оthеr hеаlth рrоblеmѕ, many оf whiсh аrе wоrѕеnеd without repairing a leaky gut. A fеw оf thеѕе аѕѕосiаtеd diѕеаѕеѕ inсludе:
Eczema, рѕоriаѕiѕ аnd several other dermatologic conditions
Pancreas dеfiсiеnсу lеаding to mаlаbѕоrрtiоn and diаbеtеѕ
Fungal аnd yeast infесtiоnѕ such аѕ candida infestation
Mаlnutritiоn ѕесоndаrу to failure of absorption оf nutriеntѕ
Sеnѕitivitу tо ѕеvеrаl chemicals and аdditivеѕ саuѕing аllеrgiеѕ
Fаtiguе, tiredness, аnd a fаilurе tо thrive in сhildrеn
Frequеnt hеаdасhеѕ аnd inаbilitу tо concentrate on wоrk
Lоѕѕ оf memory and easy fоrgеtfulnеѕѕ аrе соnѕеԛuеnсеѕ
Bowel disturbances lеаding tо diаrrhеа аnd irrеgulаr hаbitѕ
Whеn Lеаkу Gut Syndrome affects сhildrеn, thе рrоblеmѕ аrе соmроundеd bу the requirеmеnt fоr highеr lеvеlѕ of nutriеntѕ in diet fоr уоungѕtеrѕ аѕ wеll as the lоng tеrm consequences оf сhrоniс infесtiоnѕ аnd malnutrition. Vассinаtiоn has led tо a similar syndrome like lеаkу gut in some сhildrеn.
Livеr Diѕоrdеrѕ Rеѕulting From Leaky Gut
With thе liver bеing thе firѕt mаjоr barrier tо tоxinѕ thаt еntеr thе blооd ѕtrеаm thrоugh leaky gut mеmbrаnеѕ, it is nоt ѕurрriѕing that thе liver iѕ affected аt ѕоmе stage or the оthеr in реорlе with leaky gut ѕуndrоmе.
Sоmе tоxinѕ mау еѕсаре thе ѕсаvеnging еffесt of thе liver, аnd еntеr thе general circulation саuѕing harm in ѕеvеrаl tissues. But most оf thеm gеt trарреd by thе livеr, whеrе thеу are nеutrаlizеd аnd еxсrеtеd in bilе. Hоwеvеr, this increased lоаd on thе livеr can ѕоmеtimеѕ lеаd tо mаlfunсtiоn, оr even frank livеr fаilurе, thоugh these аrе extreme соmрliсаtiоnѕ that hарреn only in a very tinу minority of ѕuffеrеrѕ.
What could pass the gut lining and enter the hepatic portal vein?
- Toxins, environmental; from bacteria and viruses
- Larger, partially digested food particles
Zonulin, Bacteria secret toxins and can alter tight junctions.
The increased gut permeability happens at the microvilli, which are finger like structures and single layer of cells. The microvilli reach into the gut and have the job to let the nutrients and vitamins, extracted from digested food, into the blood stream which leads to the hepatic portal vein. This vein brings the nutrients, vitamins, and toxins into the liver for detoxification.
In a healthy gut the single cell layer of the microvilli are held together with proteins called tight junctions. When digested food reaches the microvilli, the tight junctions loosen up just so much that the nutrients can get into the blood stream. Zonulin regulate the opening and closing of the tight junctions.
The question then is How can we prevent and heal a Leaky Gut?
- Identify and Remove inflammatory foods from your diet
MRT food sensitivity test, IgG, IgM, IgE antigen blood test
- Eat organic foods if possible to avoid chemicals. At least wash fruits and vegetables with water and vinegar. Peal fruits.
- Drink enough water to prevent dehydration. Water is necessary for phase II detoxification.
- Identify and Remove pathogens in the gut, such as parasites using a stool pathogen test. Blood tests for virus antibodies. CBC with diff to check if the immune system is overactive.
- A better option would be to restore gut function with the 3 Step Gut Restoration Program.
- You also can listen to my Youtube video on the 3 Step Gut Restoration Program
- Reduce Stress: don’t over commit, learning to say NO can be very important.
- Reduce EMF exposure; turn wifi off at night (Check out my Youtube channel on this subject)
- Don’t use a cell phone and/or computer at night before you go to bed. The blue light emitted by the screen of those devices prohibit melatonin production.
- Sleep in a dark, cool room
If you have any questions, can contact me.
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Reference: Zonulin signaling http://en.wikipedia.org/wiki/Zonulin The gastrointestinal tract microbiome, probiotics, and mood. Vitetta L1, Bambling M, Alford H. Abnormal intestinal permeability and microbiota in patients with autoimmune hepatitis. Lin R1,Zhou L1,Zhang J1,Wang B1. Arthritis susceptibility and the gut microbiome. Taneja V1. Leaky gut and autoimmune diseases. Fasano A1. Gut permeability is related to body weight, fatty liver disease, and insulin resistance in obese individuals undergoing weight reduction. Damms-Machado A1, Louis S1 Abnormal Barrier Function in Gastrointestinal Disorders. Farré R1,2, Vicario M3,4,5.
Candida – Can you free yourself ?
Candida overgrowth is not recognized as a real health issue; therefore, most physicians don’t test for it.
However, you are experiencing symptoms such as:
- Brain fog, difficulty concentrating and/or focusing
- Fatigue, tired all the time
- Sugar cravings
- Sinus congestion
- Skin irritations, acne, rashes
- Depression, mood swings, even anxiety
- Vaginal itching
Everyone has Candida yeast in the gut, mouth and vagina. Candida is not all bad, as it helps with digestion and nutrient absorption. Other gut bacteria need to be kept in check, otherwise we end up with Candida overgrowth and once we have reached this point, we develop symptoms.
Causes of Candida overgrowth
Candida is called an opportunistic organism, which means it will get out of control like a child or teenager left alone at home. We need adults at home, which are other good bacteria to keep Candida in check. So, if there is an imbalance between the good and bad bacteria in the gut, called Dysbiosis, Candida will do what it does best; multiply.
This brings us to the next question:
What are the causes of Dysbiosis of the microflora?
- Toxins from the environment
- Heavy metals
- Stress, lifestyle stressors, not enough sleep, poor diet high in sugar and refined carbohydrates
- Anti-inflammatory drugs
- Adrenal issues, too much or too little cortisol
- Parasite infection
How to get rid of Candida?
Well, we never can get rid of Candida, but we can get rid of Candida overgrowth.
As a Functional Diagnostic Practitioner, I look at underlying causes of symptoms. In the case of Candida overgrowth, I know that it is not the problem, but it is the result of the underlying problem.
Most of the time, the immune system is compromised and bacterial dysbiosis in the gut, due to a lack of supervision so to speak, creates the opportunity for Candida to grow uncontrollably.
- Candida lives on sugar and refined carbohydrates. In order to starve it, food items that contain those sugars need to be eliminated.
- In regard to the dysbiosis, we need to heal the gut, which includes balancing the gut flora.
- I mentioned stressors as the cause of Candida overgrowth; therefore, we need to look at those and eliminate as many as possible.
Takeaway: if you think you have Candida overgrowth and you follow one of those protocols to kill Candida offered online, it may not work for you in the long run.
My approach as a Functional Diagnostic Practitioner:
- Starving Candida with a sugar and starch free diet.
- Eating “Real” Foods such as grass fed beef, eggs from free roaming chicken not fed with grains, replenish minerals and vitamins and healthy fats.
- Stress reduction: Identifying inside stressors such as parasites and bacterial dysbiosis and correcting the problem with the help of herbal supplements. Identifying external stressors such as the influence of a negative person in one’s life, environmental toxins.
- Sleep hygiene. Going to bed around 10pm.
- Exercise: not everyone can go to the gym 3-5 times a week. Some are just too weak to even walk around the block. Whatever exercise you can perform is the one you could start out with.
- Biofilm disrupter: this is huge. All bacteria in the gut or sinuses block the immune system from reaching it by creating a biofilm. Most of the time, biofilms are several layers thick and are hard to break open.
- Identifying pathogens and getting rid of those with herbal supplements.
- Supplementation with antifungals to kill Candida.
- Gut healing supplements: they repair the mucosal barrier in the gut lining
- Probiotics play a big role in balancing the intestinal flora; they even help to digest food and produce nutrients.
- RestorFlora contains S.boulardii or
This holistic approach to restoring balance and function in your entire body is the principle that I work with. It may not always be easy, but it is the best option to support the body in healing itself.
Contact me if you would like a free consultation
is actually a positive reaction of the body. In the case of injuries the acute inflammation helps to protect damaged regions and starts the repair.
An acute inflammation lasts only days or a couple of weeks. If the inflammation lasts longer then we talk about a chronic inflammation.
Chronic inflammation is the result of injury, auto immune processes or infections.
Leukocytes involved in the process of a chronic inflammation are monocytes and macrophages.
The problem is the production of pro-inflammatory mediators which cause tissue damage.
If we look further into the immune system involvement then we find CD4 classified immune cells. They produce cytokines, which are chemical messengers.
Other immune cells involved in the immune system response are Thymus Helper Cells for short Th. There are several branches of TH cells like the TH1, TH2, TH17 and Treg (regulatory T cells).
If you have Hashimoto’s then you probably know about TH1 or 2 dominance. TH17 pathway is often times overlooked, but is as important as the other pathways.
TH1 cells are activated in the case of microorganisms while TH2 cells protect against parasitic infections.
Interesting to know for women is probably the fact that during a pregnancy the immune system dominates shifts toward TH2.
Therefore the babies are most likely born with a th2 dominance. Once they are exposed to germs, microorganisms then the body develops the immune system and the body will balance TH1/2.
So, what is the TH17 pathway? It plays a major role in the Gastro intestinal tract. Th17 pathway will attract neutrophils and promote inflammation. Neutrophils are white blood cells and are involved in the innate immune system / meaning it is the first line of defense, acting in the case of infections but it will not cause a long lasting protective immunity in the host.
Treg cells (Regulatory T cells or suppressor cells) limit chronic inflammation by suppressing the activation of the immune system and are very important in preventing autoimmunity.
or contact me if you would like to book a free 20 minute Health Consultation.
Methylation part I
So what is methylation? It is a biochemical process which takes place continuously in every cell of the body. It is not one reaction but over one hundred reactions that occur in every cell of the body all the time. Imagine methylation cycles as wheel spinning with the help of methyl groups to drive the cycles. These methyl groups are being transferred (donated) from one chemical to another. Each of the cycles you see in this picture has a specific function which can be performed by methyl groups.
Are three hydrogen atoms and one carbon atom bonded together. Methyl groups are vital for gene expression, and normal cell replication dictated by the DNA. When sufficient methyl groups are being present, the genes can work perfectly, passing on their DNA code to the RNA in order to ensure the cells work properly.
What are the functions of Methylation?
- Regulating genetic expression, e.g. turn genes on or off
- Producing neurotransmitters such as serotonin, dopamine, and norepinephrine
- Muscle and neuron health
- Detoxification with the production of glutathione, produced in the liver.
- DNA & RNA synthesis and repair.
- Creating immune cells, such as natural killer cells and T- cells
- Myelination for the protection of nerves
- Health of the cardiovascular system
- Production of mitochondrial energy.
As you can see those functions are all very important in keeping the body healthy. If the methylation processes don’t work properly we develop symptoms and diseases.
As an example, we can take a look at the immune system which under normal circumstances protects us. When methylation problems are expressed, the immune system may not be able to perform it’s function. Say you are infected with a virus, the immune system would start an attack on it. But with certain mechanisms not working properly, the virus can stay active for a very long time, and we end up with a chronic virus infection. Epstein Barr virus is a very common infection which can result in extreme fatigue and a low grade fever. It can also cause leaky gut, and this in turn causes food intolerances. Another problem is a high homocysteine level which can cause heart disease.
The development of chronic conditions can be explained by the list of functions of methylation. If our body can’t detoxify environmental toxins, degrade excess hormones such as estrogen, can’t repair DNA, can’t protect the nerves with a healthy outer myelin sheath, a person can develop conditions such as:
Autism, Depression, Diabetes, Cancer, Parkinson’s, Alzheimer’s, Atherosclerosis, ADD, Multiple Sclerosis, Dementia, Chemical Sensitivity, Chronic Fatigue Syndrome, Alcoholism, Insomnia, Down Syndrome, Chronic Viral Infection, Neuropathy, Recurrent miscarriage, Infertility, Anxiety, Schizophrenia, Bipolar disorder, and Allergies
Now to the good news as we learn about the factors that help methylation cycles work properly.
- Nutrients such as zinc, vitamin B12 or magnesium are needed. For example: Magnesium is involved in about 300 enzyme functions.
- Healing the gut. We must have a healthy gut in order to absorb the nutrients from the food we eat.
- Clean Water without fluoride and chlorine.
- Organic food without herbicides, pesticides, chemical fertilizers.
- Stress reduction through meditation, avoiding excessive exposure to EMF (Electric Magnetic Fields) while working on the computer or using a cell phone.
- Healthy sleep habits help the body to rest and repair.
As you can see there are a lot of lifestyle factors you could try to implement on your own.
If you want to know exactly where you have methylation issues, you need to consider a gene test, such as the 23andme, as well as specific blood and urine tests.
Walk away with a new way of thinking about Health and Symptoms
the first, all spore, carotenoid rich, probiotic consortium formulation on the market.
MegaSporeBiotics a Practitioner-only product.
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We are more bacteria than human!
- 10 trillion human cells vs 100 trillion bacteria cells.
- There are over 1000 different species of commensal organisms in the GI tract out of 35,000 possible.
- Bacterial genes out number human genes 150 to 1 ( 25,000 human genes vs. 3.3 million microbial genes)
- No two individuals have the exact same composition – not even twins. Species level vast difference
- Disease is associated with a disruption to the ecology of the GI tract such as Crohn’s disease, IBS, asthma and even obesity.
- Pathogenic organisms are normal inhabitant of the GI tract such as H.pylori, staphylococcus, e.coli.
- We actually use bacterial DNA for our own metabolic functions.
What disrupts the population of probiotics in our gut?
- Birth via C-Section
- Baby formula instead of breast milk
- Antibiotic use, especially if take at a young age and always if not combined with probiotics.
- Anti-bacterial soap and hand sanitizers have a significant detrimental effect on the development of healthy GI flora.
Other Affects on the Microbiome
- Surgery , usually followed by antibitocs.
- Age, the older we get the more the microbiome declines.
- Food choices, the healthier the food choices the better the positive impact on our microbiome.
- Toxic substances, influence our gut microbiome. Fluoride in tap water, precooked foods, sodas, with ingredients such as artificial sweeteners, syrups.
- Prescription drugs, Tobacco, Alcohol
What kind of probiotics are required?
It’s important to note that the first part of the definition of a probiotic is that the microorganism has to be alive or it doesn’t fit the definition of a probiotic.
Studies by the Food Standards Agency has confirmed that more than 90 % of strains used in probiotic products today do not survive the gastric system. Thus, they are not “live microorganisms” and not probiotics.
A true probiotic has to naturally survive the gastric barrier – as MegaSporeBiotic ™ does.
- Must have a position in the microbiota – it’s important for a probiotic to be able to colonize well to afford its beneficial function. Without a spot for it, it will not be able to compete.
- Must have sufficient numbers to colonize and cause stimulation for benefit.
This is an important feature that is often overlooked. Probiotics work in large part by causing stimulation in the GI. But this stimulation can only occur if the amount of live microorganisms being administered exceeds the natural number of those same species that exist in the GI. This is a fundamental issue with most lactobacillus-and bifidobacterium- based probiotics. These strains naturally exist in the GI in numbers exceeding a trillion cells; thus supplementing in amounts even in the billions, doesn’t cause the necessary stimulation.
The strains found in MegaSporeBiotic exist in total numbers of a few million cells in the GI, thus supplementing in excess of 4 billion live cells causes massive stimulation of the GI.
, by evolution, should naturally occur in the environment (where they gain exposure to the host) and be stable both in the environment and GI tract. Ask yourself where did our Ancestors get their probiotics from? Certainly not from a health food store. They got it with the food from the earth (environment). So, any true probiotic should be found in the environment.
Survival of probiotics through gastric juices in the stomach, 20 min at pH 1-3
Summary: only 4 of 35 strains would survive to enter the large intestine and the survivors would have less than 50 % survival.
MegaSporeBiotic is the first, pharmaceutical grade probiotic formulation naturally designed to survive the harsh gastric environment and arrive at the site of action alive – ensuring full potency.
So, what’s nature’s design for supplemental probiotics?
- The most popular is Bacillus spores; also the most wildly studied and used probiotics outside of the supplement market.
- Bacillus spores were the first commercial probiotics. Were also the first prescription probiotics starting in 1958:
- Enterogermina (Sanofi-Aventis, Italy)
- Bacti-Subtil (Aventis, Pharma, France)
- Most widely used and well studied strains in humans are:
- Bacillus Subtilis
- Bacillus Licheniformis
- Bacillus Coagulans
- Bacillus Clausii
- Introducing – Patented Bacillus Indicus HU 36
Key Features of Bacterial Spores
- They form robust endospore and can withstand harsh temperatures, desiccation, low pH, gastric barriers, antibiotics, UV radiation, solvents, enzymes and even high pressures.
- They are found all over the environment (soil, vegetation, dust, rocks, aqua-environments, digestive systems of insects, marine life, mammals, etc)
- Spores remain dormant up to 50 years
- They colonize very effectively in the Human GI tract and have been found to colonize very effectively in the GI tract of several different animals.
- Are found as part of the normal human commensal flora.
- Long history of use in industries where efficacy is closely measured (pharma, agricultural)
- Extremely safe Use of probiotics are supported by evolution.
- Its use as a probiotic is evolutionarily supported – true commensal organism.
In spore forms they are transported from host to host / from the environment into the GI tract.
We don’t get the exposure to these spores as we should due to the sterile food supply.
The probiotics have 2 lifecycles / they can live outside the human host in the environment.
As soon as the spores get into the GI tract they understand where they are and they come out of the spore form and transform into vegetated, thriving cell.
Where do we get our probiotics from?
- All the lactobacillus from our mother when we pass through the birth canal as well as through the amnionic fluid, through core blood and from breast milk.
- Those species are not in the environment so humans are not designed to consume those species.
- Spores on the other hand are found all over in the environment
- Was developed by Dr. Simon Cutting, Ph.D
- The only dietary supplement probiotic that contains Bacillus Clausii – a strain tested for over 50 years.
- Contains 5 efficacious bacillus spore probiotics in the consortium – each strain is backed up by a history of use and by published science.
- Delivers over 4 billion live probiotic cells daily – a dose that matches and exceeds all prescription products of the same strains. The single most powerful spore probiotic formulation.
- Blended with a pre-biotic to enhance colonization.
- Spores produce a significant number of potent antibiotics that control bacterial over-growth in the GI tract
- Spores conduct competitive exclusion of pathogenic organisms to help maintain microbiota balance. They fight for space and nutrients to eliminate the invading species. Such as candida or c diff.
- Spores have the ability to increase the numbers of the important GI tract commensals, such as lactobacillus.
Immunemodulation means a down regulation when it’s over active or up regulation when it is under active.
- Bacillus probiotics has been shown to produce key enzymes that help the digestion of food products and alleviate bloating, cramping and discomfort. Enzymes like alpha-amylase, lactase, protease and lipase are improved with the use of Bacillus.
- Dysbiosis (i.e. the presence of harmful bacteria and the imbalance of good bacteria in the GI tract) is the main cause of digestive disorders and can be argued as being the root cause of most disease. Dysbiosis is also responsible for incomplete digestion of consumed foods. Studies have shown that Bacillus probiotics help prevent the growth of harmful bacteria and promotes the growth of beneficial bacteria – thus alleviating dysbiosis.
Key Nutrient Production
- Production of vitamins – Bacillus probiotics have been shown to produce important amounts of vitamin K and biotin in the large intestines. Absorption of these vitamins are high as they are produced at the sight of absorption.
- Bacillus also digests resistant starches and non-starch polysaccharides (is a major component of dietary fiber) to short-chain fatty acids, mainly acetate, propionate, and butyrate, which stimulates colonic blood flow and fluid and electrolyte uptake
- New Bacillus Indicus HU36 – produces high levels of carotenoids that are of the highest bioavailability.
Bacillus Subtilis HU58
- Widely used, safe and highly effective
- Produces over 12 affective antibiotics
- Makes nattokinase and vitamin K2
- Highly important for immune development and stimulation of the immune system
Bacillus Indicus HU36
- Potent immune stimulation
- Produces high levels of carotenoids – lycopene, axtaxanthin, beta-caroten, lutin.
- Produces quinols and vitamins
- The most effective antioxidants on the market.
- Most widely used probiotic drug in the world.
- Potent immune stimulator
- Antibiotic resistant for use during antibiotic treatment
- Produces antibiotic bacitracin.
- Produces protease for digestion and helps protein digestion.
- Produces whole spectrum of B vitamins and Folic acid.
- Very well studied and long history of use
- Very effective against IBS, Crohn’s.
- Produces L+ optical from of lactic acid
- Potent immune stimulation
Dose, unlike lactobacillus sp and bifidobacterium sp, bacillus spores are found in concentrations around 2 million cells in the gut.
With a dose of just over 4 billion live cells daily, megaspore offers a potent probiotic effect as the dose exceeds the endogenous species by 2000 times / highest on the market.
MegaSpore is both transient and a colonizer.
It is both, which is another unique aspect of these strains.
It is transient because it has about a 21-27 day life cycle in the digestive system. Each individual cell spends about that much time in the gut in various sections and tissues. During their time in the gut, they do attach and colonize.
They attach, they metabolize, they grow by binary fission and they alter the environment around themselves.
If you took just a single dose of Megaspore once, you will find those strains in your gut and stool samples for 21+ days. The digestive system is something like 30 ft long from end to end and it has the surface area of a professional tennis court, so this is a lot of ground to cover.
The strains have the unique ability to exist in various segments of the digestive tract and in various tissues; the mucosa and epithelium.
So when you consume a capsule, the cells move along through your digestive tract and colonize different locations. Some stay in the upper GI (small bowel), some go on to ascending colon, some to the transverse colon, some to the distal.
They attach there and start multiplying to build up their number.
But with that one does, they get fairly spread out, so additional doses are good as you do 2 things:
- You increase their numbers so they can cover more tissue and
- You get that continuous immune stimulation/modulation from the daily exposure to them. Especially in the Peyer’s patches. Peyer’s patches are organized lymphoid nodules usually found in the lowest portion of the small intestine and the ileum. They are important in immune surveillance and generate immune response within the mucosa.
Why do the bacteria leave the GI tract? They are programmed to leave the gut at some interval because it is crucial to their survival and spread. They use the environment to transfer from host to host. So they have to leave and enter back into the environment to find the next host. This is how they have spread all over the globe.
So they have it programmed in their DNA to re-sporulate and leave the body at some point. But they do leave behind some of their new cells, which will also leave about 21 days after they were created.
Nature has designed them to be consumed continuously as our ancestors did. That daily stimulation/modulation of our immune tissue by the spores is critical to immune function. Also keeping their numbers up in the gut is a big benefit to us.
Unhealthy eating combined with physical inactivity is the leading cause of death in the USA.
A diet high in calories, saturated fats, refined sodium and sugar, couple with low fiber and nutrients can lead to various health problems. Some these health problems are:
- Heart disease
- High blood pressure
- Autoimmune diseases
Years ago, our forebears cooked healthy meals from fresh produce. The food that was available to our ancestors was full of nutrition. Nowadays, the reverse is the case. The soil we grow plants in is depleted of minerals and beneficial bacteria. The use of synthetic fertilizer, herbicides and pesticides sprayed by workers in hazmat suites often genetically modified.
In addition, minerals and vitamin deficiencies often lead to illness and premature aging. Minerals are not produced in our body but need to be replenished every day. Let’s take a look at what the symptoms are when someone eats a less than optimal diet.
- Trouble sleeping through the night
- Weight gain
- Headaches, back pain, knee pain, and shoulder pain
- Digestive issues – gas, constipation, diarrhea
- Gum disease
- Tooth decay
- Bad breath
- Muscle tension
- Trouble concentrating
- Anger and irritability
- Skin rashes or eczema
- Brain fog
Foods should provide us with energy, satisfy us, be fun to eat, and keep us healthy. In addition we need to think about our gut health which includes foremost the health of our gut bacteria. We have about 2 lbs of gut bacteria which weighs as much as our brain and communicates with the brain.
Let’s take a look at what foods are beneficial for us and the micorbiome, the gut bacteria.
- Grass fed beef
- Organic raised pork
- Free roaming, natural fed poultry
- Eggs from natural fed chicken
- Butter from grass fed cow milk
- Olive Oil
- Coconut oil and butter
- Organic vegetables
- Organic fruits
- Nuts and Seeds
Now, what will happen when you start nourishing your body? The simple answer is that you probably experience less symptoms and more energy. You may be able to sleep better and through the night. You may not need to see your doctor as often anymore. And your doctor may NOT even see the need for a prescription drugs.
We can choose to support our body with nourishing food and clean water right now.
This article is for informational purposes only. Please consult your health care provider if you want to make changes to your lifestyle.
Toxins are present in the environment, drinking water, food, food containers and maybe cleaning products. Toxins can also be found in chemical ingredients that are used in personal care products. Care products we use every day such as shampoo, conditioner, hair styling products, body lotion, make up, foundation, facial creams, perfumes, and shaving cream have toxin in them. These chemicals can have impact on your body because your skin easily absorbs whatever you rub onto it – body lotion or magnesium gel.
There are certain chemicals which are often used in personal care products that could affect your health. These personal care products that contain some dangerous chemicals need be avoided. Let us look at some of these chemicals that could be hazardous to your health.
There are certain chemicals that made up Parabens and these include Methylparaben and Propylparaben. These two chemicals are found in hair products, shaving cream, body lotion and cosmetics as antimicrobial preservatives. They act as endocrine disruptor and they interfere with estrogen activity and bind to alpha and beta estrogen receptor in female. Besides, these two chemicals increase the risk of breast cancer. They cause breast cancer because parabens mainly accumulate in breast tissue.
Phthalate has Ethylparaben, 4-Hydroxybenzoic acid and many other chemicals that could be dangerous. Phthalates are used in plastic bottles because they soften the material. Every personal care product that is sold in soft containers is being contaminated with phthalates. Phthalates are also found in frequencies, paint pigments and flooring as well as in plastic milk containers.
Phthalates are also endocrine disruptor with estrogenic activity. Women who suffer from endometriosis often times have elevated levels of phthalates as well as children on the autism spectrum. Phthalates are linked to birth defects, obesity, diabetes and heart disease.
These chemicals that made up Phthalate can decrease male fertility by lowering sperm count and testosterone. However, it is important to remember that the law in the USA does not require full disclosure of fragrance mixtures. Therefore, it is hard to know if the products you are purchasing contain phthalates or not. Phthalates are fat-soluble. Foods such as butter, milk and cheeses stored in plastic container have higher amounts of Phthalates than foods that do not contain fats.
Bisphenol-A, also called BPA, is found in food containers especially food cans with epoxy lining. It can also be found even on some sales receipts. BPA is present in plastic containers with the #7 recycling code as well as in water bottles and sometimes in water supply pipes.
BPA exposure can occur through store receipts and personal care products. It often bypasses liver metabolism and thereafter enters the bloodstream directly. BPA is an endocrine disruptor with estrogenic activity. Foods such as butter, milk and cheeses stored in plastic container have higher amounts of BPA than foods that do not contain fats.
When BPA get into foods, it can cause a higher than normal risk for type II diabetes, interfere with infertility, increase the risk for cardiovascular disease, breast cancer, prostate and testicular cancer.
Perfluorinated Compounds PFC’s
These are teflon chemicals which repel oil and water and are basically indestructible. They are found in food packaging such as fast food wrappers, and of course in cookware coated with PFC’s. Furniture, carpets and clothing can be treated with PFC’s to become stain-resistance.
Effects of PFC’s on animal
PFC’s are hormone disruptors. Several studies conducted on animal revealed abnormal thyroid and testosterone levels after exposure to certain PFC’s. Other animal studies found that PFC’s can cause certain types of cancer such as kidney and testicular cancers.
According to pubmed, “Endocrine disruptors are chemicals that interfere with the hormone system and produce adverse developmental, reproductive, neurological, and immunological effects in mammals.” Further studies found that even substances that were banned a long time ago can be detected in the body of almost every tested animal and human. This can be explained by the fact that endocrine disruptors are highly lipid soluble which leads to their bio accumulation in adipose tissue. Estrogen disruptor acts on estrogen receptor sites in the cell nucleus as well as changing the expression of genes by binding to DNA.
Why chemicals are difficult to remove from the body
The liver is the number one detoxification organ in humans’ body. It works in two phases to get rid of waste products to keep us healthy. Phase I is the Hydroxylation phase where molecules such as hormones, neurotransmitter, drugs and toxins become activated. The enzyme CYP450 converts such molecules and those can act as carcinogens and free radicals.
In Phase II detoxification the liver inactivates and detoxifies the substances from Phase I. The waste products are sent via the bile into the intestines and can get re-absorbed into the liver. This is the stage it gets difficult to remove chemicals from the body.
Problems with the detoxification process can occur when we lack phytonutrients because we eat a poor diet. Fried foods, processed foods are especially harmful to the body. What we need are fresh vegetables and fruits, grass fed beef and free roaming chicken for proteins, fat, carbohydrates, vitamins, minerals and fiber.
Another reason why chemicals are difficult to get rid of has to do with gene variations that we are born with, which down or up regulate enzymatic activities. These enzymes metabolize estrogens.
Metabolism of estrogens is a complex process and can be monitored with a combination of gene test and a urine hormone test which also measures the metabolites of estrogen and other hormones.
What can you do to reduce your exposure to toxins?
- Buy cotton clothing and wash them before wearing.
- Get natural flooring such as wool carpet.
- Purchase organic foods and wash them in a solution of vinegar and water before eating.
- Use essential oils as perfume.
- Protect yourself by eating natural, nutritious foods.
- Drink clean water and get a water filter for the shower and kitchen.
- Purchase natural cosmetic products, makeup, shampoo, body lotion etc.
If you are looking to get more information on how to reduce toxins generally, login to www.ewg.org The Environmental Working Group’s
Charles, Ak, Darbre, Pd. Combinations of parabens at concentrations measured in human breast tissue can increase proliferation of MCF-7 human breast cancer cells. J Appl Toxicol. 2013; 33(5); 390-8
Dodge LE, Williams PL, Williams, Missmer SA, Souter I, Calafat AM, Hauser R, Associations, between paternal urinary phthalate metabolite concentrations and reproductive outcomes among couples seeking fertility treatment. Reprod Toxicol. 2015; Oct 6
Lin J, Chen W, Zhu H, Wang C. Determination of free and total phthalates in commercial whole milk products in different packaging materials by gas chromatography-mass spectrometry. J Dairy Sci. 2015; Oct 7
Naraanan KB, Ali M, Barclay BJ, et al. Disruptive environmental chemicals and cellular mechanisms that confer resistance to cell death. Carinogenesis. 2015; 36; S89-110
Urinary Paraben Concentrations and Ovarian Aging among Women from a Fertility Center / Kristen W. Smith Irene Souter, Irene Dimitriadis, Shelley Ehrlich, Paige L. Wiliams, Antonia M. Calafat and Russ Hauser
Probiotics being used to Re-Seed the Gut
The hypothesis of the probiotic industry is that we can re-seed the gut with the good bacteria. They use the same model as we would re-seed a bare spot in our lawn. You take a few grass seeds, sprinkle it on the dirt, water, fertilize and it grows back to a full lush lawn.
Taking probiotics orally with factory grown strains of bacteria to re-seed the gut is simply
You probably heard about the Human Microbiome Project, which taught us a lot about the microbiota which we didn’t know before.
What do we know about Probiotics?
- We know that they keep the bad bacteria in check
- We know that we receive ALL of the lactobacillus and bifidobacterium species that we currently have in our gut, from our mother. They are called commensal bacteria.
- We know that we receive those bacteria during child birth by passing through the vagina, through mother’s milk, through skin to skin contact with our mother, father and other family member.
- We know that after 838 days after birth, we have our own, unique set of gut microbes, which is basically our adult microbiota.
- We know that food influences the gut microbiota for the better or worse.
- We know that our lifestyle influences the microbiome. Stress would be a negative influence, while relaxation would be a positive.
- We know that antibiotics kill all kinds of strains in the gut, the good and the bad.
How did our Ancestors get their Probiotics?
- Our ancestors lived from the land as hunters and gatherers
- They searched for roots. They had to dig up the dirt to get to them and were exposed to lots and lots of bacteria and spores that lived in the dirt.
- They did not go home and scrub their hands and cleaned their fingernails to get rid of bacteria
- They did not use anti-bacterial soap or gels
- They ate the animals they hunted which ate the natural grass
- So our ancestors were exposed to environmental organisms every day
You may know that we humans are more bacteria then human.
Let me explain. We have about 10 trillion human cells in our body and 100 trillion bacterial cell.
So Bacterial genes outnumber human genes 150 to 1 (25,000 human genes vs. 3.3 million microbial genes.
One of these species is the Bacillus species.
They live in the human gut and use the environment in spore form as a place to transfer from host to host.
This means they can live in an aerobic, which is the environment, as well as in an anaerobic world, the GI tract.
Bacteria love the GI tract; it is warm, moist, and provides lots of food.
Benefit of a healthy microbiome in particular the Bacillus Species
- They train and modulate the immune system by stimulating the lymphoid tissue in the gut. Bacillus species help to improve T and B- cell function and the adaptive immune system and reduce inflammatory processes.
- They help us digest food. Protease, peptidase, lipase, cellulose, amylase, lipase, lactase and pectinase are probably familiar names to you. You probably have a digestive enzyme supplement at home that includes all or some of those. Guess what, Bacillus species produce those digestive enzymes I listed above. They also digest starches and non-starch polysaccharides (cellulose from plants such as broccoli) without producing any gas.
- They help balance the microbiota. Bacillus species keep harmful bacteria in check and they produce nutrients that are designed specifically to feed the healthy microbes. In other words, they create a healthy environment in our gut where the good guys can flourish and do their job while the bad guys are being eliminated and held in check.
- They produce nutrients in the gut. B vitamins are produced by bacillus species. As you know those are important for the nervous system as well as key methylation functions. Vitamin K2 is also produced by gut bacteria which is important for heart and artery health but mostly used by the bacteria themselves.
- They produce short-chain fatty acids (SCFAs) which are very important to keep the gut healthy. They dampen inflammation and prevent leaky gut.
Megaspore is the first probiotic that includes 5 critical Bacillus species in spore form.
As we just learned Bacillus species live as spores in the environment and come out of the spore form in the GI tract.
The improvement in health, gut function, even behavioral changes of children, elimination of allergies we see in people using Megaspore is remarkable.
For even more information and to purchase MegaSpore click here
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